Impact of an Etoposide Chemotherapy Shortage on Patients With Extensive-Stage Small-Cell Lung Cancer: Results of a Natural Experiment.

Claire BrowneToufic AyoubNadeesha SamarasingheSyed HussainiAndrew WarnerMorgan Black David A Palma Jacques RaphaelSara KuruvillaPhillip S Blanchette

Published in: JCO oncology practice (2024)

This study demonstrated increased hospitalization, and decreased PFS, among patients with ES-SCLC treated with alternate chemotherapy regimens during an IVES. The impact of cancer drug shortages can be harmful, and optimizing a more secure drug supply with mitigation strategies is warranted.

Keyphrases

small cell lung cancer
locally advanced
papillary thyroid
climate change
adverse drug
squamous cell
squamous cell carcinoma
drug induced
emergency department
radiation therapy
chemotherapy induced
brain metastases
rectal cancer
electronic health record
lymph node metastasis