Wnt signalling inhibits adipogenesis in orbital fibroblasts from patients with Graves' orbitopathy.

Sang Joon JungYeon Jeong ChoiTae Kwann ParkSang Earn WooBo-Yeon KimJin Sook Yoon Sun Young Jang

Published in: The British journal of ophthalmology (2021)

These results indicate that Wnt signalling inhibits adipogenesis in OFs from patients with GO and non-GO participants. Further studies are required to examine the potential of Wnt signalling as a target for therapeutic strategies.

Keyphrases

cell proliferation
stem cells
metabolic syndrome
adipose tissue
insulin resistance