A novel ZIC3 mutation in a Chinese family with heterotaxy and multiple types of congenital heart defect.

Yu Wang Xiaohui DaiHanmin LiuJin PengJiao Chen

Published in: Prenatal diagnosis (2022)

ZIC3 encodes a highly conserved zinc-finger protein that is highly correlated with CHDs. The present study of a Han Chinese family with CHDs expands the mutation spectrum of ZIC3 and provides further evidence that ZIC3 plays important roles in CHDs.

Keyphrases

transcription factor
protein protein
small molecule