Irritability in young people with copy number variants associated with neurodevelopmental disorders (ND-CNVs).
Jessica H HallSamuel J R A Chawnernull nullJeanne WolstencroftDavid SkusePeter A HolmansMichael J OwenMarianne B M van den BreePublished in: medRxiv : the preprint server for health sciences (2023)
Irritability is an important aspect of the clinical picture in young people with ND-CNVs. This work shows that genetic variation is associated with irritability in young people with ND-CNVs, independent of psychiatric comorbidities or IQ impairment. Clinicians should be aware of this increased risk to inform management and interventions.