Enumeration of circulating endothelial cell frequency as a diagnostic marker in aortic valve surgery - a flow cytometric approach.
Anton SabashnikovKlaus NeefVera ChesnokovaLeonie WegenerKathrin GodthardtMaximilian SchernerElmar W KuhnAntje-Christin DeppeMeike LauerKaveh EghbalzadehMohamed ZeriouhParwis B RahmanianJens WippermannFerdinand Kuhn-RégnierNavid MadershahianThorsten WahlersAlexander WeymannYeong-Hoon ChoiPublished in: Journal of cardiothoracic surgery (2017)
The new flow cytometric approach might be a robust and reliable method for CEC enumeration. Initial results show that CEC frequency is a valid clinical marker for the assessment of pre-operative risk, invasiveness of surgical procedure and clinical outcome. Further studies are necessary to validate the practical clinical usefulness and the potential superiority compared to conventional markers.
Keyphrases
- aortic valve
- minimally invasive
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve replacement
- endothelial cells
- circulating tumor cells
- aortic stenosis
- coronary artery bypass
- heart failure
- coronary artery disease
- risk assessment
- percutaneous coronary intervention
- left ventricular
- case control