N-Glycosylation Profiles of Immunoglobulin G and Future Cardiovascular Events.
Rosangela Akemi HoshiBranimir PlavšaYanyan LiuIrena Trbojević-AkmačićRobert J GlynnPaul M RidkerRichard D CummingsIvan GudeljGordan LaucDemler V OlgaSamia MoraPublished in: Circulation research (2024)
An IgG N-glycan profile was associated with incident CVD in 2 populations (primary and secondary prevention), involving an agalactosylated glycan associated with increased risk of CVD, while several digalactosylated and sialylated IgG glycans associated with decreased risk. An IgG glycan score was positively associated with future CVD.