A Co(TAML)-based artificial metalloenzyme for asymmetric radical-type oxygen atom transfer catalysis.

Eva J MeeusNico V IgaretaIori Morita Thomas R Ward Bas de Bruin Joost N H Reek

Published in: Chemical communications (Cambridge, England) (2023)

We show that the incorporation of a biotinylated Co(TAML) cofactor within streptavidin enables asymmetric radical-type oxygen atom transfer catalysis with improved activity and enantioselectivity.

Keyphrases

electron transfer
molecular dynamics
solid state