Transcriptome Profile of Next Generation Sequence Data Related to Inflammation on Nasopharyngeal Carcinoma Cases in Indonesia.
Digdo SudigyoGisti RahmawatiDicka Wahyu SetiasariRisky Hiskia PoluanSalsabila Luthfi SesotyosariTirta WardanaCita HerawatiDidik Setyo HeriyantoSagung Rai Indrasari- AfiahayatiIndwiani AstutiSofia Mubarika HaryanaPublished in: Asian Pacific journal of cancer prevention : APJCP (2020)
There are 13 genes that play a role in the inflammatory process in Nasopharyngeal Carcinomafrom a sample of the Indonesian population. Genes CXCL9, CXCL10, CXCL11, MYLK2, COL20A1, MYH2, ACTC1, HTR2A, NGF, TRPA1, PRKCG, and ADCY8 have been upregulated and ALOX15 has been downregulated. These genes play a role in the Inflammation Mediated by Chemokine and Cytokine Signaling pathways, Inflammatory Mediator Regulation of TRP Channels, and Toll-Like Receptor Signaling.
Keyphrases
- toll like receptor
- oxidative stress
- genome wide
- bioinformatics analysis
- genome wide identification
- nuclear factor
- inflammatory response
- signaling pathway
- immune response
- dna methylation
- gene expression
- single cell
- genome wide analysis
- hypertrophic cardiomyopathy
- epithelial mesenchymal transition
- rna seq
- left ventricular
- cell proliferation
- atrial fibrillation
- deep learning