Nickel-Catalyzed Reductive Vinylation of Chloro-hexahydropyrroloindoline Derivatives with Vinyl Triflates.

This work emphasizes facile construction of C-3a vinyl substituted hexahydropyrrolidinoindolines based upon Ni-catalyzed reductive coupling of chloro-hexahydropyrroloindoline derivatives with a wide range of alkyl-decorated vinyl triflates. The remarkable compatibility of sterically hindered branched vinyl groups is highlighted.