Reconstitution of norovirus-specific T cell responses following hematopoietic stem cell transplantation in patients with inborn errors of immunity and chronic norovirus infection.
Jessica Durkee-ShockAriella CohenNaseem MaghzianGloria PezzellaMariah Jensen-WachspressAnna HostalKarenna BartonKrista GanglerBlachy J Dávila SaldañaNatthawan ChaimongkolCatherine M BollardStanislav V SosnovtsevJeffrey CohenBianca M NagataDerron A AlvesRajarshi GhoshBryce A SeifertAlexandra FreemanCorina GonzalezLuigi D NotarangeloKim Y GreenMichael D KellerPublished in: The Journal of infectious diseases (2024)
This report is the first to demonstrate reconstitution of norovirus-specific T cell immunity after HSCT closely temporally aligned with clearance of CNI suggesting that cellular immunity is sufficient for norovirus clearance.