Characterization of Patients with Metastatic Renal Cell Carcinoma Experiencing Complete Response to First-Line Therapies: Results from the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC).
Kosuke TakemuraVishal NavaniMatthew S ErnstJ Connor WellsLuis MezaSumanta K PalJae-Lyun LeeHaoran LiNeeraj AgarwalAjjai S AlvaAaron R HansenNaveen S BasappaBernadett SzabadosThomas PowlesBen TranChristopher M HockingBenoit BeuselinckTakeshi YuasaToni K ChoueiriDaniel Y C HengPublished in: The Journal of urology (2022)
The CR rate was not as high in the real-world population as in the clinical trial population. Among those who experienced CR, several adverse clinicopathological features were more frequently observed in the IO-based cohort than in the TKI cohort. CR was an indicator of favourable OS.