Efficacy of omalizumab in children, adolescents, and adults with severe allergic asthma: a systematic review, meta-analysis, and call for new trials using current guidelines for assessment of severe asthma.

Daniel Pilsgaard HenriksenUffe BodtgerKirsten SideniusNiels MaltbaekLars PedersenHanne MadsenEhm A AnderssonOle NorgaardLouise K MadsenBo L Chawes

Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2020)

Omalizumab provides clinically relevant improvements in exacerbation rate among children, adolescents, and adults and in OCS-reduction among adults. New studies incorporating a guideline-approached definition of severe asthma are warranted.

Keyphrases

young adults
chronic obstructive pulmonary disease
systematic review
physical activity
case control
allergic rhinitis
lung function
clinical practice
drug induced