Acute myocardial dysfunction in lupus: outcomes in Asian Indians.
Aadhaar DhooriaAtit GawalkarKrishna SantoshAjay BahlAdarsh MbGsrsnk NaiduShefali SharmaAman SharmaSanjay JainArghya ChattopadhyayPublished in: Clinical rheumatology (2020)
In this small series of patients of SLE with acute myocardial dysfunction, we report a significant in-hospital mortality due to infections. Many of the patients who died had elevated procalcitonin at presentation. A diligent search for infection seems prudent in lupus patients who present with acute myocardial dysfunction. Key Points • In patients of SLE with acute myocardial dysfunction who were treated with immunosuppression, there was significant short-term mortality due to infections. • This mortality was associated with elevated procalcitonin at baseline and may suggest some of them had pre-existing hidden sepsis. • A prudent search for infections in these patients before immunosuppression may help to decrease short-term mortality.
Keyphrases
- end stage renal disease
- systemic lupus erythematosus
- liver failure
- newly diagnosed
- ejection fraction
- chronic kidney disease
- left ventricular
- respiratory failure
- risk factors
- disease activity
- cardiovascular events
- intensive care unit
- skeletal muscle
- cardiovascular disease
- patient reported outcomes
- metabolic syndrome
- adipose tissue
- atrial fibrillation
- insulin resistance
- weight loss
- case report