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Decrease of cocaine, but not heroin, self-administration and relapse by the tyrosine kinase inhibitor masitinib in male Sprague Dawley rats.

A Belin-RauscentJ LacosteO HermineA MoussyB J EverittDavid Belin
Published in: Psychopharmacology (2018)
The present findings suggest masitinib, a drug with proven efficacy in CNS disorders, could represent a novel treatment for cocaine addiction provided its influence on the reinforcing and incentive properties of the drug is confirmed.
Keyphrases
  • adverse drug
  • blood brain barrier
  • prefrontal cortex
  • emergency department
  • combination therapy
  • electronic health record
  • smoking cessation