Augmented insulin secretory response in early pregnancy.
Camille E PoweLarraine P Huston PresleyJoseph J LocascioPatrick M CatalanoPublished in: Diabetologia (2019)
The insulin secretory response increases markedly in early pregnancy, prior to and independent of changes in insulin sensitivity. Circulating hormones may mediate this metabolic adaptation. Identifying mediators of this physiological effect could have therapeutic implications for treating hyperglycaemia during and outside of pregnancy.