Preclinical Evaluation of Safety and Biodistribution of Red Cell Microparticles: A Novel Hemostatic Agent.
Ashish K RehniVibha ShuklaHever Navarro QueroCarlos BidotConner R HaaseEnsign Anise A CraneShivam G PatelSebastian KochYeon S AhnWenche JyKunjan R DavePublished in: Journal of cardiovascular pharmacology and therapeutics (2019)
Our study indicates that RMP administration appears not to have any negative impact on the parameters studied and did not produce thrombosis in heart, brain, and lungs. However, more detailed long-term studies confirming the safety of RMP as a hemostatic agent are warranted.