Molecular subtype, biological sex and age shape melanoma tumour evolution.

M LotzT BuddenS J FurneyAmaya Virós

Published in: The British journal of dermatology (2020)

These data indicate that the contribution of environmental damage to melanoma likely extends beyond genetic damage to affect cell division. Sex and age determine the final mutational composition of melanoma.

Keyphrases

skin cancer
oxidative stress
single cell
basal cell carcinoma
genome wide
electronic health record
big data
stem cells
machine learning
copy number
risk assessment
mesenchymal stem cells
artificial intelligence
deep learning