Optic nerve hypoplasia in miniature poodle dogs: A preliminary genetic and candidate gene association study.

Doreen BeckerJessica K NiggelSue Pearce-KellingRonald C RiisGustavo D Aguirre

Published in: Veterinary ophthalmology (2019)

Pedigree analysis did not reveal the inheritance pattern. There is no evidence of association of the evaluated candidate genes with ONH; therefore, the screened candidate genes can provisionally be ruled out as causally associated with the disease.

Keyphrases

optic nerve
genome wide
copy number
mitochondrial dna
optical coherence tomography
dna methylation
gene expression
transcription factor
data analysis