Serological testing for SARS-CoV-2 antibodies in clinical practice: A comparative diagnostic accuracy study.

Michael P Horn Hulda R JonsdottirDaniel BriggerLauro DamontiFranziska Suter-RinikerOlga EndrichTanja K FroehlichMartin FiedlerCarlo R LargiadèrJonas MarschallBenjamin WeberAlexander Eggel Michael Nagler

Published in: Allergy (2022)

The diagnostic accuracy of serological tests for SARS-CoV-2 antibodies varied remarkably in clinical practice, and the sensitivity to identify patients with previous COVID-19 deviated substantially from the manufacturer's specifications. The data presented here should be considered when using such tests to estimate the infection burden within a specific population and determine the likelihood of protection against re-infection.

Keyphrases

sars cov
clinical practice
respiratory syndrome coronavirus
electronic health record
risk factors
machine learning
data analysis