Cu(II)/PTABS-Promoted, Chemoselective Amination of HaloPyrimidines.
Vikram PhulwaleHarshita ShetKrishna Chaitanya GunturuSmruti Rekha RoutRambabu DandelaSuyog AdhavAnant R KapdiPublished in: The Journal of organic chemistry (2024)
Chemoselective amination is a highly desired synthetic methodology, given its importance as a possible strategy to synthesize various drug molecules and agrochemicals. We, herein, disclose a highly chemoselective Cu(II)-PTABS-promoted amination of pyrimidine structural feature containing different halogen atoms.