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Titration of anti-IL-5 biologics in severe asthma: an open-label randomised controlled trial (the OPTIMAL study).

Marianne Baastrup SoendergaardAnne-Sofie BjerrumLinda Makowska RasmussenSofie Lock-JohanssonOle HilbergSusanne HansenAnna von BulowCeleste Porsbjerg
Published in: The European respiratory journal (2024)
This study serves as a proof of concept for titration of anti-IL-5 biologics in patients with severe asthma with clinical control on treatment, and the OPTIMAL algorithm provides a potential framework for individualising dosing intervals in the future.
Keyphrases
  • machine learning
  • study protocol
  • risk assessment
  • climate change