Response to Comment on "Molecular and neural basis of contagious itch behavior in mice".

Devin M Barry Yao-Qing Yu Yan HaoXue-Ting LiuZhou-Feng Chen

Published in: Science (New York, N.Y.) (2017)

Liljencrantz et al report the failure of observing contagious itch behavior using mice injected with histamine as the demonstrators. Analysis of their results shows that the histamine model is limited by inadequate frequency and duration of scratching bouts required for contagious itch test. To streamline the contagious itch test, the screen paradigm is highly recommended.

Keyphrases

atopic dermatitis
high fat diet induced
high throughput
type diabetes
wild type
metabolic syndrome
insulin resistance
single cell