Magnetic Resonance Images Implicate That Glymphatic Alterations Mediate Cognitive Dysfunction in Alzheimer Disease.

Jung-Lung HsuYi-Chia WeiCheng-Hong TohIng-Tsung HsiaoKun-Ju LinTzu-Chen YenMing-Feng LiaoLong-Sun Ro

Published in: Annals of neurology (2022)

Glymphatic system activity may act as a significant mediator in AD-related cognitive dysfunction even after adjusting for multiple covariates and gray matter volumes. ALPS-index may provide useful disease progression or treatment biomarkers for patients with AD as an indicator of modulation of glymphatic activity. ANN NEUROL 2022.

Keyphrases

magnetic resonance
mild cognitive impairment
optical coherence tomography
magnetic resonance imaging
combination therapy
machine learning
replacement therapy