Mild ovarian stimulation with letrozole plus fixed dose human menopausal gonadotropin prior to IVF/ICSI for infertile non-obese women with polycystic ovarian syndrome being pre-treated with metformin: a pilot study.
Giuseppe D'AmatoAnna Maria CaringellaAntonio StanzianoClementina CantatoreSimone PaliniEttore CaroppoPublished in: Reproductive biology and endocrinology : RB&E (2018)
The present study suggests that the use of letrozole as adjuvant treatment to MS protocols for IVF may be an effective alternative to CS protocols for non-obese PCOS patients pre-treated with metformin, as it provides comparable IVF outcome without requiring high FSH dose, and avoiding supraphysiological estradiol levels.
Keyphrases
- polycystic ovary syndrome
- pregnancy outcomes
- newly diagnosed
- end stage renal disease
- adipose tissue
- metabolic syndrome
- weight loss
- type diabetes
- chronic kidney disease
- ejection fraction
- endothelial cells
- early stage
- insulin resistance
- mass spectrometry
- multiple sclerosis
- prognostic factors
- peritoneal dialysis
- ms ms
- patient reported outcomes
- bariatric surgery
- combination therapy
- smoking cessation
- replacement therapy