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Endogenous Production of IL1B by Breast Cancer Cells Drives Metastasis and Colonization of the Bone Microenvironment.

Claudia TulottaDiane V LefleyKaty FreemanWalter Martin GregoryAndrew M HanbyPaul R HeathFaith NutterJeremy Mark WilkinsonAmy R Spicer-HadlingtonXinming LiuSteven M J BradburyLisa HambleyVictoria CooksonGloria AlloccaMarianna Kruithof de JulioRobert E ColemanJanet E BrownIngunn HolenPenelope D Ottewell
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)
Pharmacologic inhibition of IL1B has potential as a novel treatment for breast cancer metastasis.
Keyphrases
  • breast cancer cells
  • stem cells
  • bone mineral density
  • combination therapy
  • risk assessment
  • human health
  • bone loss