Outcome of fetuses with congenital cytomegalovirus infection and normal ultrasound at diagnosis: systematic review and meta-analysis.
Danilo Italo Pio BucaDaniele D I MascioGiuseppe RizzoA GiancottiA D'AmicoMartina LeombroniA MakatsaryaAlessandra FamiliariM LiberatiL NappiM E FlaccoL ManzoliL J SalomonG ScambiaFrancesco D'AntonioPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)
In fetuses with congenital CMV infection in which no anomalies are detected on prenatal ultrasound or MRI, the risk of adverse postnatal outcome is lower than that reported previously in the published literature when not considering the role of antenatal imaging assessment. The results from this review also highlight the potential role of MRI, even in fetuses with no anomalies detected on ultrasound, as an anomaly can be detected exclusively on MRI in about 6% of cases. The findings from this study could enhance prenatal counseling of pregnancies with congenital CMV infection with normal prenatal imaging. © 2020 International Society of Ultrasound in Obstetrics and Gynecology.
Keyphrases
- magnetic resonance imaging
- pregnant women
- contrast enhanced
- gestational age
- high resolution
- preterm birth
- systematic review
- diffusion weighted imaging
- contrast enhanced ultrasound
- ultrasound guided
- computed tomography
- preterm infants
- emergency department
- pregnancy outcomes
- risk assessment
- magnetic resonance
- human immunodeficiency virus
- photodynamic therapy
- antiretroviral therapy
- meta analyses
- hiv testing
- adverse drug