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Molecular Characterization of Malignant Renal Epithelioid Angiomyolipoma: A Review of Two Cases.

Rayan RammalDimitrios KorentzelosJohn M SkaugenGabriela M Quiroga-Garza
Published in: American journal of clinical pathology (2023)
These findings highlight the molecular landscape of malignant renal EAML and expand on the existing literature suggesting a role for TP53 and ATRX alterations in malignant progression of these tumors. The presence of synchronous benign and malignant tumors within the same patient offers a unique opportunity to directly compare the molecular alterations, further supporting the association with aggressive behavior.
Keyphrases
  • systematic review
  • single cell
  • renal cell carcinoma