A prospective evaluation of photorefractive intrastromal cross-linking for the treatment of low-grade myopia.

Epi-on PiXL may become a safe and effective non-ablative treatment for low-grade myopia. The effect is augmented by high oxygen environment and remains stable for 12 months. The initial ocular irritation is acceptable with a 4-mm treatment zone. The present results justify further clinical studies on PiXL, including refinements of the technique and long-term results.