Association of the APOE gene variants with depression in type 2 diabetes.
Zeynab Nickhah KlashamiArash YaghoobiNekoo PanahiMahsa M AmoliPublished in: Journal of diabetes and metabolic disorders (2023)
Our results showed that the apoe4 allele and apoe4 carrier status significantly reduced the risk of depression among patients with T2DM. Further studies are needed to unravel the complex role of the APOE gene in depression among patients with diabetes.
Keyphrases
- cognitive decline
- high fat diet
- type diabetes
- copy number
- depressive symptoms
- sleep quality
- genome wide
- mild cognitive impairment
- insulin resistance
- glycemic control
- gene expression
- adipose tissue
- dna methylation
- metabolic syndrome
- genome wide identification
- skeletal muscle
- transcription factor
- physical activity
- genome wide analysis