Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART.

Overall, the use of IPD often impacted the coefficient estimates, but not sufficiently as to necessitate altering the final recommendations of the 2018 WHO Guidelines. Future work should examine the features of a network where adjustments will have an impact, such as how much IPD is required in a given size of network.