A comparison of Zika and dengue outbreaks using national surveillance data in the Dominican Republic.
Leigh Robert BowmanJoacim RocklövAxel KroegerPiero OlliaroRonald SkewesPublished in: PLoS neglected tropical diseases (2018)
Evidence suggests little impact of existing dengue immunity on reported attack rates of Zika at the population level. Confounding of R0 and incident risk calculations by sex-specific over-reporting can alter the reliability of epidemiological metrics, which could be addressed using associated proxy syndromes or conditions to explore seemingly sex-skewed incidence. The findings indicate that community awareness campaigns, through influencing short-term health seeking behaviour, remain the most plausible mechanism behind increased reporting among women of reproductive age, although biological susceptibility cannot yet be ruled out. Media campaigns and screening are therefore recommended for women of reproductive age during Zika outbreaks. Future research should focus on clinical Zika outcomes among dengue seropositive individuals.
Keyphrases
- zika virus
- aedes aegypti
- dengue virus
- mental health
- public health
- polycystic ovary syndrome
- healthcare
- adverse drug
- pregnancy outcomes
- cardiovascular disease
- risk factors
- molecular dynamics
- infectious diseases
- big data
- adipose tissue
- electronic health record
- health information
- type diabetes
- current status
- quality improvement
- machine learning
- insulin resistance
- social media
- metabolic syndrome