Prediagnostic body size and risk of amyotrophic lateral sclerosis death in 10 studies.
Éilis J O'ReillyMolin WangHans-Olov AdamiAlvaro AlonsoLeslie BernsteinPiet A van den BrandtJulie BuringSarah DaughertyDennis DeapenD Michal FreedmanDallas R EnglishGraham G GilesNiclas HåkanssonTobias KurthCatherine SchairerElisabete WeiderpassAlicja WolkStephanie A Smith-WarnerPublished in: Amyotrophic lateral sclerosis & frontotemporal degeneration (2018)
These findings confirm somewhat conflicting, underpowered evidence that adiposity is inversely associated with ALS. We newly demonstrate that weight-gain during adulthood is strongly predictive of lower ALS risk.