One-Pot anti-Michael Regio- and Stereoselective Hydroamination of Activated N -Allenamides.

N -Allenamides, substituted by an ester at the γ-position, were obtained through addition of terminal ynamides with ethyl diazoacetate under copper catalysis for the first time. Regio- and stereoselective hydroamination of those activated N -allenamides provided exclusively E -configured captodative enamimes through a one-pot anti-Michael addition. Numerous ynamides as well as various secondary amines were adapted in this process.