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Health-related quality of life in rectal cancer patients undergoing neoadjuvant chemoradiation with delayed surgery versus short-course radiotherapy with immediate surgery: a propensity score-matched cohort study.

Alice M CouwenbergJohannes P M BurbachMartijn P W IntvenEsther C J ConstenAnandi H W SchiphorstAnke B SmitsNiels A T WijffelsJoost T HeikensMiriam KoopmanWilhelmina M U van GrevensteinHelena M Verkooijen
Published in: Acta oncologica (Stockholm, Sweden) (2019)
In rectal cancer patients, CRT-DS may induce a stronger decline in short-term QOL than SCRT-IS. From 12 months onwards, QOL domains, symptoms and sexual interest in male patients were comparable between the groups. However, emotional functioning remained higher after SCRT-IS than after CRT-DS.
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