The Urine-to-Plasma Urea Concentration Ratio is associated with eGFR and eGFR decline over time in a population cohort.
Dusan PetrovicLaura-Gabriela Sánchez-LozadaBelén PonteMenno PruijmTanguy CorreJean-Pierre GhobrilYassine BouatouDaniel AckermannBruno VogtMurielle BochudPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)
This study provides evidence that the U/P-urea-ratio is an early marker of kidney function decline in the general adult population. Urea is easy to measure with well-standardized techniques and at low cost. Thus, the U/P-urea-ratio could become an easily available tubular marker for evaluating renal function decline.