Cerebrospinal fluid metabolites in tryptophan-kynurenine and nitric oxide pathways: biomarkers for acute neuroinflammation.
Jingya YanUnnikrishnan KuzhiumparambilAshvin BandodkarSushil BandodkarRussell C DaleShanlin FuPublished in: Developmental medicine and child neurology (2020)
The kynurenine/tryptophan and anthranilic acid/3-hydroxyanthranilic acid ratios hold great potential as biomarkers of neuroinflammation. Elevation of the asymmetric dimethylarginine/arginine ratio in acute brain inflammation shows dysregulation of the nitric oxide pathway.
Keyphrases
- nitric oxide
- liver failure
- cerebrospinal fluid
- respiratory failure
- nitric oxide synthase
- cerebral ischemia
- traumatic brain injury
- hydrogen peroxide
- lipopolysaccharide induced
- drug induced
- aortic dissection
- oxidative stress
- lps induced
- ms ms
- hepatitis b virus
- resting state
- intensive care unit
- subarachnoid hemorrhage
- extracorporeal membrane oxygenation
- multiple sclerosis