Metformin causes cancer cell death through downregulation of p53-dependent differentiated embryo chondrocyte 1.

Shu-Man Hsieh LiShu-Ting LiuYung-Lung ChangChing-Liang HoShih-Ming Huang

Published in: Journal of biomedical science (2018)

The involvement of DEC1 provides new insight into the positive or negative functional roles of p53 in the metformin-induced cytotoxicity in tumor cells.

Keyphrases

stress induced
cell death
papillary thyroid
high glucose
squamous cell
diabetic rats
cell proliferation
signaling pathway
drug induced
cell cycle arrest
lymph node metastasis
pregnancy outcomes
squamous cell carcinoma
young adults
pregnant women