DHP23002 as a next generation oral paclitaxel formulation for pancreatic cancer therapy.
Eunseo JangMinhee SonJunhee JangIn-Hyun LeeSol KimTaejun KwonYong-Hyun JeonWoo-Suk KohKil-Soo KimSang Kyoon KimPublished in: PloS one (2019)
Oral chemotherapy with DHP23002 showed excellent absorption in animals owing to a strong antitumor activity in a pancreatic cancer mouse model. This demonstrates that paclitaxel is largely distributed and persists for a prolonged period at the tumor site owing to oral DHP23002 administration.