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DHP23002 as a next generation oral paclitaxel formulation for pancreatic cancer therapy.

Eunseo JangMinhee SonJunhee JangIn-Hyun LeeSol KimTaejun KwonYong-Hyun JeonWoo-Suk KohKil-Soo KimSang Kyoon Kim
Published in: PloS one (2019)
Oral chemotherapy with DHP23002 showed excellent absorption in animals owing to a strong antitumor activity in a pancreatic cancer mouse model. This demonstrates that paclitaxel is largely distributed and persists for a prolonged period at the tumor site owing to oral DHP23002 administration.
Keyphrases
  • cancer therapy
  • mouse model
  • drug delivery
  • chemotherapy induced
  • locally advanced
  • rectal cancer