MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1.

Sung-Tau ChouHsuan-Yu PengKuan-Chi MoYuan-Ming HsuGuan-Hsun WuJenn-Ren HsiaoSu-Fang LinHorng-Dar WangShine-Gwo Shiah

Published in: Journal of experimental & clinical cancer research : CR (2019)

This study was the first to demonstrate that betel nut alkaloid may recruit DNMT3B to regulate miR-486-3p/DDR1 axis in oral cancer andmiR-486-3p and DDR1 may serve as potential therapeutic targets of oral cancer.

Keyphrases

dna methylation
gene expression