Radiomics Analysis of Brain [ 18 F]FDG PET/CT to Predict Alzheimer's Disease in Patients with Amyloid PET Positivity: A Preliminary Report on the Application of SPM Cortical Segmentation, Pyradiomics and Machine-Learning Analysis.
Pierpaolo AlongiRiccardo LaudicellaFrancesco PanasitiAlessandro StefanoAlbert ComelliPaolo GiacconeAnnachiara ArnoneFabio MinutoliNatale QuartuccioChiara CupidiGaspare ArnoneTommaso PiccoliLuigi Maria Edoardo GrimaldiSergio BaldariGiorgio Ivan RussoPublished in: Diagnostics (Basel, Switzerland) (2022)
The results obtained in this preliminary study support advanced segmentation of cortical areas typically involved in early AD on FDG PET/CT brain images, and radiomics analysis for the identification of specific high-order features to predict Amyloid deposition and final diagnosis of AD.