Increase in perfused boundary region of endothelial glycocalyx is associated with higher prevalence of ischemic heart disease and lesions of microcirculation and vascular wall.
Alexander Y GorshkovMarina V KlimushinaSergei A BoytsovAlexander Y KotsNadezhda G GumanovaPublished in: Microcirculation (New York, N.Y. : 1994) (2019)
Thus, PBR can be considered a new highly reproducible and promising marker candidate for non-invasive diagnostics of IHD and cerebral atherosclerosis suggesting important role of microcirculation in development and progression of cardiovascular diseases.