Correlation of Cytomegalovirus (CMV) Disease Severity and Mortality With CMV Viral Burden in CMV-Seropositive Donor and CMV-Seronegative Solid Organ Transplant Recipients.
Jacqueline M McBrideDaniel SheinsonJenny JiangNicholas Lewin-KohBarbara G WernerJennifer K L ChowXiaoning WuJorge A TavelDavid R SnydmanPublished in: Open forum infectious diseases (2019)
Using specimens from studies preceding the antiviral prophylaxis era, CMV viral load was associated with severe CMV disease and death, supporting CMV viral load quantification as a proxy for CMV disease severity and disease-associated mortality end points in solid organ transplantation.