Use of synthetic oligonucleotides for determination of HTLV-1 proviral load by real-time PCR: a helpful alternative approach in the clinical management.
Larissa Melo BandeiraMarco Antonio Moreira PugaVanessa Salete de PaulaLuiz Henrique Ferraz DemarchiG G C LichsJ A DomingosRivaldo Venâncio da CunhaS N O UeharaAna Rita Coimbra Motta CastroPublished in: Journal of applied microbiology (2020)
HTLV-1 PVL determination using synthetic oligonucleotides standard curve by qPCR could be a helpful alternative for the laboratories that monitor infected patients as an important prognostic factor in HTLV-1-associated diseases progression. Also, it can decrease costs and overcome the biological limitations of the plasmid curve.