Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma.

Weipu MaoKeyi WangWentao ZhangShuqiu ChenJinbo XieZongtai ZhengXue LiNing ZhangYuanyuan ZhangHaimin ZhangBo PengXudong YaoJianping CheJunhua ZhengMing ChenWei Li

Published in: Journal of experimental & clinical cancer research : CR (2022)

Our findings suggested that SLERCC is a promising therapeutic target and that plasmid-encapsulated nanomaterials targeting transmembrane metastasis markers may open a new avenue for the treatment in RCC.

Keyphrases

renal cell carcinoma
escherichia coli
crispr cas
minimally invasive
long non coding rna
cancer therapy
combination therapy
drug delivery