Optimized Tibial Nerve Stimulation Partially Reduces Visceral Hypersensitivity in Rats Mediated via Autonomic and Opioid Mechanisms.

Liu Qin Jiang Shengai ZhangNina ZhangJiande D Z Chen

Published in: Neuromodulation : journal of the International Neuromodulation Society (2021)

TNS with parameters of 14 Hz, 330 μsec, and 40% motor threshold is effective in improving visceral hypersensitivity in rodent models of colonic hypersensitivity via the modulation of autonomic and opioid mechanisms.

Keyphrases

drug induced
chronic pain
pain management
heart rate variability
heart rate
insulin resistance
total knee arthroplasty
skeletal muscle
ulcerative colitis