Elucidating pathways to pediatric obesity: a study evaluating obesity polygenic risk scores related to appetitive traits in children.

Timothy J Renier Dabin YeumJennifer A EmondReina K LansiganGrace A BallarinoDelaina D Carlson Ruth J F LoosDiane Gilbert-Diamond

Published in: International journal of obesity (2005) (2023)

Genetic obesity risk significantly predicted appetitive traits, which partially mediated the association between genetic obesity risk and BMI in children. These findings build a clearer picture of pathways leading to pediatric obesity.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
weight gain
type diabetes
high fat diet induced
genome wide
young adults
body mass index
gene expression
skeletal muscle
childhood cancer