Lentinan confers protection against type 1 diabetes by inducing regulatory T cell in spontaneous non-obese diabetic mice.

Tijun WuTing LeiFandi NiuBin QianPeng SunNan YangJing PangHongliang MeiXiaoai ChangFang ChenYunxia ZhuYating LiFu-Gen WuYaqin ZhangTing LeiXiao Han

Published in: Nutrition & diabetes (2023)

LNT was capable of stimulating the production of Treg cells from naive CD4 + T cells, which implies that LNT exhibits therapeutic values as a tolerogenic adjuvant and may be used to reverse hyperglycaemia in the early and late stages of T1D.

Keyphrases

type diabetes
dendritic cells
regulatory t cells
early stage
glycemic control
adipose tissue
weight loss
hiv infected
metabolic syndrome
cardiovascular disease
insulin resistance
obese patients
bariatric surgery