Gram-negative bacillary meningitis in an immunocompetent adult.
Aniruddha RaySatyaki BasuSouradeep DasAtanu ChandraPublished in: BMJ case reports (2023)
Escherichia coli is a rare cause of community-acquired meningitis comprising about 1% of adult cases. However, it is a common pathogen in neonatal meningitis and in nosocomial setting (especially after penetrating craniocerebral injury or subsequent to neurosurgical procedures). We report a middle-aged woman, who was admitted with features of acute meningitis and subsequent investigations revealed E. coli growth in cerebrospinal fluid culture. The case is distinctive as no additional predisposing risk factors associated with gram-negative bacillary meningitis (traumatic brain injury, neurosurgical procedures, malignancy, immunosuppressive therapy, HIV infection, chronic alcoholism and diabetes) were present. She was treated with intravenous antibiotics as per sensitivity reports and discharged in clinically stable condition, without any residual neurological deficit.
Keyphrases
- cerebrospinal fluid
- gram negative
- multidrug resistant
- escherichia coli
- traumatic brain injury
- acinetobacter baumannii
- middle aged
- klebsiella pneumoniae
- drug resistant
- type diabetes
- healthcare
- cardiovascular disease
- mental health
- liver failure
- low dose
- high dose
- intensive care unit
- metabolic syndrome
- drug induced
- staphylococcus aureus
- candida albicans
- single cell
- mesenchymal stem cells
- antiretroviral therapy
- case report
- hepatitis b virus
- adipose tissue
- methicillin resistant staphylococcus aureus
- blood brain barrier
- cell therapy
- aortic dissection
- weight loss
- replacement therapy
- subarachnoid hemorrhage
- severe traumatic brain injury