Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing.

Julio Gutiérrez Karel H M van Wely Carlos Martinez-A

Published in: Cell & bioscience (2022)

These results offer insight into the distinct vulnerabilities in mouse organs following impairment of the mRNA processing machinery, and could aid understanding of human health dependence on accurate mRNA metabolism.

Keyphrases

human health
risk assessment
binding protein
early onset
high resolution
mass spectrometry
germ cell