Global reported impacts of COVID-19 on lymphoma patients and the emerging clinical management approaches in response to the ongoing pandemic.
Esther K ElliottRobert HensenLarisa M HauptLyn R GriffithsPublished in: European journal of haematology (2023)
The Coronavirus disease 2019 (COVID-19) pandemic has dramatically impacted the health risk and management of patients with lymphoma. Clinical evaluations on the impact of COVID-19 on lymphoma patients are currently limited however, reports have shown a correlation with specific variants and more severe COVID-19 complications and higher mortality rates relative to other disease states and age-matched populations. During peak pandemic periods this created a concerning management problem for clinicians and raised the question of how different immunocompromised states increase COVID-19-associated risk and provided insights into how immunity interacts with the circulating variant, including the effects of low virulent variants in vaccinated lymphoma populations. Treatment management approaches, polymerase chain reaction tests and rapid antigen screening guidelines have been offered in an attempt to reduce the risk of harm to lymphoma patients, particularly prior to and following bone marrow or stem cell transplant. Here we systematically review the current literature to provide a novel global perspective on incidence, mortality, management and rapid antigen test (RAT) screening for COVID-19, in patients with various subtypes of lymphoma. Furthermore, lessons learned from emerging variants that continue to inform evolving lymphoma management and public health policies are addressed across these associated matters.
Keyphrases
- coronavirus disease
- sars cov
- diffuse large b cell lymphoma
- end stage renal disease
- public health
- ejection fraction
- stem cells
- chronic kidney disease
- bone marrow
- newly diagnosed
- prognostic factors
- health risk
- respiratory syndrome coronavirus
- type diabetes
- peritoneal dialysis
- copy number
- systematic review
- mesenchymal stem cells
- risk factors
- oxidative stress
- cardiovascular disease
- coronary artery disease
- cardiovascular events
- dna methylation
- risk assessment
- patient reported outcomes
- electronic health record
- extracorporeal membrane oxygenation
- adverse drug
- drug induced